The A47 near Wisbech is closed in both directions on the Norfolk/Cambridgeshire border following a serious collision.
Emergency services are at the scene.
The road remains closed in both directions between the A1101 (Elm High Road) and the B198 (Cromwell Road) near Wisbech (west) due to a collision.
Traffic is being diverted via local routes.
Road users in the area are advised to allow extra time for their journey.
The road is likely to be closed for some time while accident investigators continue their inquiries.
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